Chicago Med season 4: Predictions about the new season

CHICAGO MED -- "The Tipping Point" Episode 320 -- Pictured: (l-r) Torrey DeVitto as Dr. Natalie Manning, Nick Gehlfuss as Dr. Will Manning -- (Photo by: Elizabeth Sisson/NBC)
CHICAGO MED -- "The Tipping Point" Episode 320 -- Pictured: (l-r) Torrey DeVitto as Dr. Natalie Manning, Nick Gehlfuss as Dr. Will Manning -- (Photo by: Elizabeth Sisson/NBC) /

What’s going to happen in Chicago Med season 4? One Chicago Center makes its predictions about what’s ahead in the new Chicago Med season.

The new season of Chicago Med is coming to NBC in just over a week, which means it’s time for our annual pre-season predictions of what to expect from Gaffney Chicago Medical Center!

When we left off, the third One Chicago show dropped multiple cliffhangers. Would Dr. Natalie Manning (Torrey DeVitto) accept Dr. Will Halstead’s (Nick Gehlfuss) marriage proposal? Would one of the doctors leave the hospital? Did the hospital’s serial killer finally die? There are so many questions that all need answers.

So we’re predicting what’s coming up in Chicago Med season 4, based on what we’ve learned over the summer and what we know about the show over the past three seasons. Will these possibilities make you more excited about the upcoming season?

Here are our Chicago Med predictions:

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1) Natalie will say yes to Will

There are reasons for Natalie to both accept Will’s proposal and reject it. But the biggest reason for her to say yes is that Chicago Med fans might riot if she doesn’t.

There are always two sides to consider when it comes to any plot decision: what makes sense on screen, and what makes sense off-screen. This goes more toward the latter.

The show has invested three whole seasons into the Manstead relationship; it won’t throw all that away now. And this is the primary ship for the entire show. It’s simply a more pragmatic, and more flashy, choice if Natalie says yes.

After all, the show’s not promising that they’ll end up getting married—just that they’ll be engaged. Keep that in mind.

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2) Reese leaves the hospital

Dr. Sarah Reese (Rachel DiPillo) is going to be ticked off at the start of Chicago Med season 4. She will lose her father and/or find out that her father killed at least one person. And based on the way she behaved during the third season, she’s going to blame Dr. Daniel Charles (Oliver Platt) in some fashion.

Reese had blinders on when it came to her father, and even if she didn’t, she has a perfectly valid right to be angry with Charles for not telling her the truth—even if he has a perfectly valid reason for protecting her. It’s a lose-lose situation.

And if we know anything about Reese, it’s that she runs away from problems. We saw that in the second season, when Charles found her working at a coffee shop rather than accepting her first match in Pathology. There’s no reason to believe she’ll do anything else this time, when the issue is even bigger, so expect her to bail out of Chicago Med when she feels that she’s got no one to trust.

3) Connor and Ava will hook up again

Speaking of relationships, Dr. Connor Rhodes (Colin Donnell) and Dr. Ava Bekker (Norma Kuhling) may be off when Chicago Med season 4 starts but they won’t stay that way. Last season’s finale made sure we saw that shot of Ava crying when Connor left, and Connor was jealous when his dad hit on Ava.

Though their romantic relationship has hardly been developed, every single sign points to them carrying torches for each other, and Chicago Med‘s writers clearly favor them as a pairing in how they’ve been writing for Ava. So while they’re not a couple now, we predict they will be before midseason—though with as much as they fight, it could be an even bumpier road than the one Manstead is on.

Next. See our exclusive Chicago Med set photos. dark

What do you think is going to happen in Chicago Med season 4? Leave your own predictions in the comments, and don’t miss the season premiere in less than two weeks!

Chicago Med returns to NBC on Sept. 26.