Chicago Fire season 8, episode 4 preview: Infection, Part 1

CHICAGO FIRE -- "Infection, Part I" Episode 805 -- Pictured: Kara Killmer as Sylvie Brett -- (Photo by: Matt Dinerstein/NBC)
CHICAGO FIRE -- "Infection, Part I" Episode 805 -- Pictured: Kara Killmer as Sylvie Brett -- (Photo by: Matt Dinerstein/NBC) /

What should fans watch for in tonight’s Chicago Fire? Get ready for Infection, Part 1 with our Chicago Fire season 8, episode 4 preview.

The next Chicago Fire kicks off the One Chicago crossover that fans have been waiting for since the new season started, which means that it’s going to be packed with story as it sets the table for the entire event.

“Infection, Part 1” opens on a big, terrifying note as a tailgate featuring characters from not just Fire, but Chicago PD and Chicago Med, turns potentially deadly. A flesh-eating bacteria is loose in the Windy City!

That would be frightening enough, but as with every One Chicago event, there’s a villain behind the problem (because otherwise, the other two shows wouldn’t have anyone to catch).

So what does the crossover have in store for Firehouse 51?

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Unsurprisingly, “Infection” puts paramedics Sylvie Brett (Kara Killmer) and Emily Foster (Annie Ilonzeh) front and center. They’re the best qualified to deal with a medical situation, which means more Brett for the second week in a row, after she got center stage in last week’s episode “Badlands.”

Ambulance 61 will be called upon quite a bit as the infection spreads, and one thing to keep an eye on is how Brett continues to step back into the team. As she retakes her role as Paramedic in Charge, this is a big challenge to get thrown into almost right away.

One could say it’s even bigger than last season’s three-show crossover. An apartment building fire, while terrifying, is something paramedics are used to dealing with; an epidemic of deadly bacteria isn’t the kind of thing that they’d normally encounter.

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Another thing to watch for, according to Chicago Fire star Miranda Rae Mayo, are the special effects that come with the term “flesh-eating.” The One Chicago crew has gone above and beyond in making this threat creepy.

“It was fun,” Miranda enthused when we spoke to her before the crossover. “Our special effects makeup department did an incredible job. So that was fun.

“But the whole thing has just been very, very grand—like the production value, the shots, everything,” she added. “I think that our audience is going to be so pleased and just blown away by the quality of this three-hour event.

“Every single one of our directors was so specific about what they wanted and the shots and how it looked, and all of our writers, and we’re still getting pages; just wanting to make it the best that it can be. So it was really fun. It was really fun to work on something where everybody was so excited about making it great.”

Hopefully this crossover won’t be too hard on Stella, since the last time all three shows met, she ended up at Chicago Med in critical condition. But she and the rest of the firehouse will have their hands full in this episode, and because it’s only Part 1, expect that the story will get worse by the end of the hour.

Next. Our full One Chicago crossover preview. dark

For the latest Chicago Fire season 8 spoilers and news, plus more on the entire series, follow the Chicago Fire category at One Chicago Center.