Chicago Med season 5, episode 4 preview: Infection, Part 2

CHICAGO MED- "Infection Part II" Episode 506 -- Pictured: (l-r) Torrey DeVitto as Dr. Natalie Manning, Tracy Spiridakos as Det. Hailey Upton -- (Photo by: Liz SissonNBC)
CHICAGO MED- "Infection Part II" Episode 506 -- Pictured: (l-r) Torrey DeVitto as Dr. Natalie Manning, Tracy Spiridakos as Det. Hailey Upton -- (Photo by: Liz SissonNBC) /

What should fans watch for in tonight’s Chicago Med? Get ready for Infection, Part 2 with our Chicago Med season 5, episode 4 preview.

This week’s Chicago Med moves back an hour later in order to facilitate the first One Chicago crossover of the season, so will this be a chance for the medical drama to get more attention?

The episode is the second part of the “Infection” event, and fans already have an idea of what they’re going to see it in: the doctors and nurses trying to treat people who have been infected by the flesh-eating bacteria, and prevent the disease from spreading.

Official photos from the network prove that there’ll be quarantines, for even more drama.

But the bigger question for One Chicago fans is how much of a role will Chicago Med actually play in this crossover?

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Those photos also mostly feature characters from Chicago PD. If you didn’t know it was a crossover, you’d be forgiven for thinking this was an episode of PD, instead of Med.

And our medical drama has a history of being the third wheel in most crossovers. If it’s a three-show crossover, the doctors usually have the least screen time as they mostly treat patients. And then there are the two-show crossovers that they’re not even included in.

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Since this plot is about a medical crisis, one would hope that it means the Chicago Med characters get a sizeable part of the story. After all, they’re the team most qualified to handle what’s going on!

But we’ll have to watch and see if that actually is the case, or if they continue to play supporting roles to the characters from Chicago PD and Chicago Fire.

Whatever happens, viewers can expect another massive event. Yaya DaCosta, who portrays April Sexton, told us about how huge of an undertaking “Infection” was; not just this episode but all of the storyline.

“This was a very intense one,” she explained when we spoke to her ahead of the crossover. “I feel the most involved all around. The most crossing over [between shows], and for good reason. I think the audience is just going to be wowed, glued to the screen for three hours. It’s really, really

Her co-star Brian Tee, who portrays April’s colleague and boyfriend Dr. Ethan Choi, agreed with that sentiment. “I think it has been difficult because it’s going to be so big,” he said. “And I think everyone wants to get it right. And I think we have the ability to be able to do so.

“It’s difficult because we’re working with three different shows, trying to tell one particular story. And [there are] schedules and all that sort of stuff,” he continued. “We have the luxury to be able to create a universe such as this and create the best product out there.

“So the fact that it’s difficult is probably a good thing. That means people are actually working and wanting to tell a really incredible, impactful story, especially during our crossovers.”

Being the second part of the event, there should be plenty going on in this episode of Chicago Med and opportunities for its characters to shine. Since it’s a medical story, there’s really no excuse not to showcase the hospital. Hopefully that’s exactly what happens!

Next. Our full One Chicago crossover preview. dark

For the latest Chicago Med season 5 spoilers and news, plus more on the entire series, follow the Chicago Med category at One Chicago Center.